Competing risk bias in prognostic models predicting hepatocellular carcinoma occurrence: impact on clinical decision making
Hamish Innes, Philip Johnson, Scott McDonald, Victoria Hamill, Alan Yeung, John Dillon, Peter Hayes, April Went, Stephen Barclay, Andrew Fraser, Andrew Bathgate, David Goldberg, Sharon Hutchinson
Existing models predicting hepatocellular carcinoma (HCC) occurrence do not account for competing risk events, and thus may overestimate the probability of HCC. Our goal was to quantify this bias for patients with cirrhosis and cured hepatitis C.